Application

α-Ketoglutaric acid may be used as an analytical reference standard for the quantification of the analyte in the following:Human plasma samples using gas-chromatography coupled to mass spectrometry.Beer samples using high-performance liquid chromatography with UV detection, and further confirmed by high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS).Fruits and vegetables using HPLC-MS/MS.

General description

α-Ketoglutaric acid, an α-ketoacid, is identified as a potential, renal cell carcinoma (RCC) biomarker via urinary metabolomic profiling. It plays an important role in living beings as an angiogenesis suppressor.